best quality High Purity 8047-67-4 top purity Iron sucrose

Anemia is an important complication of chronic renal failure. The application of genetic recombinant erythropoietin has greatly improved the patient’s anemia. However, many dialysis patients have no response or poor efficacy to erythropoietin therapy. Iron deficiency is the most common cause of erythropoietin resistance. 
The reason is that proper iron supplementation is essential to obtain the curative effect of erythropoietin. 
There are two ways of iron supplementation, oral and intravenous. Patients who still have moderate anemia after oral iron are tested for serum ferritin, serum iron, folic acid and vitamin B12, and it is found that folic acid and vitamin B12 are in the body of anemia patients. The serum ferritin and serum iron are significantly lower than normal. After long-term oral iron administration, the serum ferritin and serum iron in the patient's blood are still significantly insufficient. This may cause the renal replacement therapy patients to use erythropoietin but HB 
An important reason for non-compliance. Before intravenous iron use, most patients use oral iron supplementation. Studies have shown that oral iron is difficult to achieve or maintain the treatment goals of renal anemia. The reasons may include insufficient intake, and the average daily iron intake is only 10~ 
15mg, of which only 10%-20% can be absorbed; too much loss, such as repeated blood tests, residual blood in the dialyzer and tubing, gastrointestinal bleeding, etc.; the application of rhEPO increases the body's demand for iron.

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